14041 (5)

Psilocybin Item No. 14041

$80

Psilocybin (Item No. 14041) is an analytical reference standard categorized as a tryptamine.1,2 It induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.2 Psilocybin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

WARNING This product is not for human or veterinary use.

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Product Description References

1. Nichols, D.E., and Frescas, S. Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis 6, 935-938 (1999).

2. Glatfelter, G.C., Pottie, E., Partilla, J.S., et al. Structure–activity relationships for psilocybin, baeocystin, aeruginascin, and related analogues to produce pharmacological effects in mice. ACS Pharmacol. Transl. Sci. 5(11), 1181-1196 (2022).

Product Citations

Kato, K., Kleinhenz, J.M., Shin, Y.-J., et al. Psilocybin treatment extends cellular lifespan and improves survival of aged mice. NPJ Aging 11(1), 55 (2025).

Sekssaoui, M., Bockaert, J., Marin, P., et al. Antidepressant-like effects of psychedelics in a chronic despair mouse model: is the 5-HT2A receptor the unique player? Neuropsychopharmacology 49(4), 747-756 (2024).

Glatfelter, G.C., Pottie, E., Partilla, J.S., et al. Structure–activity relationships for psilocybin, baeocystin, aeruginascin, and related analogues to produce pharmacological effects in mice. ACS Pharmacol. Transl. Sci. 5(11), 1181-1196 (2022).

Hesselgrave, N., Troppoli, T.A., Wulff, A.B., et al. Harnessing psilocybin: Antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice. Proc. Natl. Acad. Sci. USA 118(17), e2022489118 (2021).

Formal Name

3-[2-(dimethylamino)ethyl]-1H-indol-4-ol, 4-(dihydrogen phosphate)

CAS Number

520-52-5

Molecular Formula

C12H17N2O4P

Formula Weight

284.3

Purity

≥98%

Formulation(Request formulation change)

A crystalline solid

Solubility(Learn about Variance in Solubility)

DMSO: 1 mg/mlPBS (pH 7.2): 2 mg/ml

λmax

222, 268, 290 nm

SMILES

CN(C)CCC1=CNC2=C1C(OP(O)(O)=O)=CC=C2

InChi Code

InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)

InChi Key

QVDSEJDULKLHCG-UHFFFAOYSA-N

Regulatory Information

DEA Schedule

I

Shipping & Storage Information

Storage

-20°C

Shipping

Room temperature in continental US; may vary elsewhere

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